Directing systemic oncolytic viral delivery to tumors via carrier cells☆
نویسندگان
چکیده
منابع مشابه
Directing systemic oncolytic viral delivery to tumors via carrier cells.
The systemic administration of oncolytic virus (OV) is often inefficient due to clearance of the virus by host defense mechanism and spurious targeting of non-cancer tissues through the bloodstream. Cell mediated OV delivery could hide the virus from host defenses and direct them toward tumors: Mesenchymal and neural stem cells have been described to possess tumor-homing ability as well as the ...
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ژورنال
عنوان ژورنال: Cytokine & Growth Factor Reviews
سال: 2010
ISSN: 1359-6101
DOI: 10.1016/j.cytogfr.2010.02.004